Standard rig has been Marshall DSL 401 combo (40W, 1x12), and sometimes "Speaker Emulated DI Out", and sometimes speaker out to Egnater Tourmaster 212x. I have quite enjoyed the Vox Valvetronix too, though a relatively low end product (12AX7 preamp + modeling amps) it makes some pretty decent sounds, especially for coming up with all kinds of different tones.
Favorite guitars are custom Carvin DC150 (neck thru, birds-eye maple neck) and Gibson Nighthawk (a Gibson/Fender hybrid if there ever was one), BC Rich Bich (vintage), and Ibanez RGT42 (SuperStrat shredder, neck thru).
Don't use pedals much, but I like the Fulltone OCD and use it on the Marshall clean channel sometimes.
However, after the "Purist vs. Pragmatist" Tone Thread debate on RR right before "the crash", I decided to finally upgrade Guitar Rig (to GR5) so I could use it on my newer Windows machine. Wow, what incredible options and capabilities! I have been exploring that for weeks, and may well end up just going with GR for many things recording-wise. I was also still able to use my RigKontrol 2 (from GR2) foot controller with GR5. I'm really impressed a Mfr continued to support older hardware going forward! Really impressed with what they have done.